Best practices the following have been disabled on each server

· Windows Firewall

· TCP Chimney

· IPV6

· RSS

· Network DMA

- Autotunning

Syntax: netsh interface tcp set global autotuninglevel=disabled

You need to set permissions on each mailbox database for BES when running in an Exchange 2010 env.

Unable to reply to email on BES device

I was getting the following errors in the application logs on the BES server:

"xxx"

So a restart of the server resolved the issues, and I was able to reply to email.

Messages stuck in Exchange 2010 queue for certain email domains

I set the FQDN of the SMTP connector on the HT and disabled autotuning via the folowing syntax:

netsh interface tcp set global autotuninglevel=disabled